(19)

(11)

EP 0 303 668 A1

(12)

(43) Date of publication: 22.02.1989 Bulletin 1989/08 (21) Application number: 88902162.0 (22) Date of filing: 03.03.1988

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) C12N 15/ 75( . ) C12R 1/ 07( . ) C12N 1/ 20( . ) C12P 21/ 00( . ) C12R 1/ 125( . ) (86) International application number: PCT/GB1988/000159 (87) International publication number: WO 1988/006622 (07.09.1988 Gazette 1988/20)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 03.03.1987 GB 19870004908 (71) Applicant: CELLTECH LIMITED Slough Berkshire SL1 4EN (GB)	(72) Inventor: MOUNTAIN, Andrew 4 St. Michaels Cottages Wokingham Berkshire RG11 3DU (GB) (74) Representative: Hallybone, Huw George, et al  CARPMAELS AND RANSFORD 43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)