(19)
(11) EP 0 306 525 A1

(12)

(43) Date of publication:
15.03.1989 Bulletin 1989/11

(21) Application number: 88903550.0

(22) Date of filing: 18.03.1988
(51) International Patent Classification (IPC): 
A61K 31/ 195( . )
A61K 31/ 415( . )
A61K 31/ 44( . )
A61P 3/ 08( . )
A61K 31/ 40( . )
A61K 31/ 42( . )
A61K 31/ 50( . )
(86) International application number:
PCT/US1988/000814
(87) International publication number:
WO 1988/006887 (22.09.1988 Gazette 1988/21)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 20.03.1987 US 19870028512

(71) Applicant: ALCON LABORATORIES, INC.
Fort Worth, TX 76115 (US)

(72) Inventor:
  • YORK, Billie, M., Jr.
    Crowley, TX 76036 (US)

(74) Representative: Jaeger, Klaus, Dipl.-Chem. Dr. 
Jaeger, Böck & Köster Patentanwälte Postfach 1620
D-82121 Gauting
D-82121 Gauting (DE)

   


(54) USE OF ALDOSE REDUCTASE INHIBITORS TO ENHANCE INSULIN SENSITIVITY IN DIABETES MELLITUS