(19)
(11) EP 0 308 910 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
30.08.1989 Bulletin 1989/35

(43) Date of publication A2:
29.03.1989 Bulletin 1989/13

(21) Application number: 88115512.1

(22) Date of filing: 21.09.1988
(51) International Patent Classification (IPC)4C07F 15/00
// A61K31/28
(84) Designated Contracting States:
CH DE ES FR GB IT LI

(30) Priority: 25.09.1987 JP 241542/87

(71) Applicant: SS PHARMACEUTICAL CO., LTD.
Chuo-ku, Tokyo 103 (JP)

(72) Inventors:
  • Yokoi, Koichi
    Kashiwa-shi Chiba-ken (JP)
  • Mogi, Kinichi
    Abiko-shi Chiba-ken (JP)
  • Irinoda, Kazuhiko
    Chiba-shi Chiba-ken (JP)
  • Kohya, Hidehiko
    Narita-shi Chiba-ken (JP)
  • Sato, Susumu
    Inba-gun Chiba-ken (JP)
  • Katori, Tatsuhiko
    Kitasouma-gun Ibaraki-ken (JP)

(74) Representative: Wächtershäuser, Günter, Prof. Dr. 
Patentanwalt, Tal 29
80331 München
80331 München (DE)


(56) References cited: : 
   
       


    (54) Novel platinum complex


    (57) A platinum complex having a superior antitumor activity is discolsed. The platinum complex has a structure represented by the formula:

    wherein A and B independently represent a lower alkanoyloxy group which may have a halogen atom substituent, or in combination represent a group:

    wherein R₁ and R₂ independently represent a hydrogen atom, a hydroxyl group, or a lower alkyl group, or in combination with each other and with the adjacent carbon atom a cyclobutane ring, and R₃ represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, a halogen atom, a sulfo group, or nitro group.





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