(19)
(11)
EP 0 318 500 A1
(12)
(43)
Date of publication:
07.06.1989
Bulletin 1989/23
(21)
Application number:
87905380.0
(22)
Date of filing:
31.07.1987
(51)
International Patent Classification (IPC):
C12N
15/
09
( . )
C12N
5/
10
( . )
C12N
15/
85
( . )
C07K
14/
755
( . )
C12N
15/
67
( . )
(86)
International application number:
PCT/US1987/001871
(87)
International publication number:
WO 1988/000975
(
11.02.1988
Gazette 1988/04)
(84)
Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
(30)
Priority:
01.08.1986
US 19860893115
(71)
Applicant:
GENETICS INSTITUTE, INC.
Cambridge, MA 02140 (US)
(72)
Inventors:
KAUFMAN, Randal, J.
Boston, MA 02116 (US)
ISRAEL, David
Arlington, MA 02174 (US)
(74)
Representative:
VOSSIUS & PARTNER
Postfach 86 07 67
D-81634 München
D-81634 München (DE)
(54)
HIGH LEVEL INDUCIBLE EXPRESSION OF HETEROLOGOUS GENES