(19)
(11) EP 0 318 935 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
29.08.1990 Bulletin 1990/35

(43) Date of publication A2:
07.06.1989 Bulletin 1989/23

(21) Application number: 88119911.1

(22) Date of filing: 29.11.1988
(51) International Patent Classification (IPC)4: C07F 9/38, C07F 9/40, A61K 31/66
(84) Designated Contracting States:
AT BE CH DE ES FR GB GR IT LI LU NL SE

(30) Priority: 30.11.1987 US 126372
14.10.1988 US 256221

(71) Applicant: WARNER-LAMBERT COMPANY
Morris Plains New Jersey 07950 (US)

(72) Inventors:
  • Bigge, Christopher Franklin
    Ann Arbor Michigan 48103 (US)
  • Drummond, James Thomas
    Ypsilanti Michigan 48197 (US)
  • Gregor, Vlad Edward
    Ann Arbor Michigan 48105 (US)
  • Johnson, Graham
    Ann Arbor Michigan 48103 (US)
  • Pavia, Michael Raymond
    Ann Arbor Michigan 48104 (US)

(74) Representative: Mansmann, Ivo 
Gödecke AG Patentwesen Mooswaldallee 1-9
79090 Freiburg
79090 Freiburg (DE)


(56) References cited: : 
   
     
    Remarks:
    Claims for the following Contracting States: ES + GR.
     


    (54) Substituted alpha-amino acids having pharmaceutical activity


    (57) The present invention is novel substituted a-amino acids, pharmaceutical compositions, methods of use, and preparations therefore having utility for treating disorders which benefit from blockade of aspartate and glutamate receptors.





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