(19)
(11) EP 0 321 497 A1

(12)

(43) Date of publication:
28.06.1989 Bulletin 1989/26

(21) Application number: 87906262.0

(22) Date of filing: 10.09.1987
(51) International Patent Classification (IPC): 
A61K 38/ 55( . )
A61P 9/ 00( . )
C07K 5/ 02( . )
C07K 5/ 065( . )
A61K 38/ 00( . )
A61P 5/ 38( . )
A61P 9/ 12( . )
C07K 5/ 06( . )
C07K 14/ 81( . )
(86) International application number:
PCT/US1987/002264
(87) International publication number:
WO 1988/002374 (07.04.1988 Gazette 1988/08)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 30.09.1986 US 19860913490
30.10.1986 US 19860925830
27.01.1987 US 19870007079

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)

(72) Inventors:
  • SCHOSTAREZ, Heinrich, J.
    Portage, MI 49002 (US)
  • HESTER, Jackson, B., Jr.
    Galesburg, MI 49053 (US)
  • SAWYER, Tomi, K.
    Portage, MI 49002 (US)

(74) Representative: Perry, Robert Edward, et al 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) RENIN INHIBITORY PEPTIDES HAVING NOVEL C-TERMINAL MOIETIES