(19)

(11)

EP 0 326 545 A1

(12)

(43) Date of publication: 09.08.1989 Bulletin 1989/32 (21) Application number: 87903217.0 (22) Date of filing: 13.05.1987

(51) International Patent Classification (IPC):  A01N 43/ 16( . ) A01N 63/ 02( . ) C08B 37/ 00( . ) C12P 19/ 04( . ) A01N 63/ 00( . ) C07H 1/ 08( . ) C12N 1/ 20( . ) C12R 1/ 01( . ) (86) International application number: PCT/AU1987/000137 (87) International publication number: WO 1987/006796 (19.11.1987 Gazette 1987/25)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 13.05.1986 AU 19860005868 (71) Applicants: THE AUSTRALIAN NATIONAL UNIVERSITY Acton, Australian Capital Territory 2601 (AU) MACQUARIE UNIVERSITY North Ryde, NSW 2113 (AU)	(72) Inventors: ROLFE, Barry, Garth Curtin, ACT 2605 (AU) CHEN, Hancai 10 Masson Street Turner, ACT 2601 (AU) DJORDJEVIC, Steven, Phillip Manuka, ACT 2603 (AU) REDMOND, John, William West Ryde, NSW 2114 (AU) BATLEY, Michael Beecroft, NSW 2119 (AU) (74) Representative: Collier, Jeremy Austin Grey, et al  J.A.KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)