ATRIOPEPTINS, GUANYLATE CYCLASE ACTIVATORS, AND PHOSPHODIESTERASE INHIBITORS AS TREATMENT FOR GLAUCOMA, HYDROCEPHALUS AND CEREBRAL EDEMA (CRANIAL FLUID VOLUME DYSFUNCTION) - Patent 0341264

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(11)

EP 0 341 264 A1

(12)

(43)	Date of publication:
	15.11.1989 Bulletin 1989/46

(21)	Application number: 88901976.0

(22)	Date of filing: 22.01.1988

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International Patent Classification (IPC):

A61K 31/ 21^{( . )}
A61K 31/ 495^{( . )}
A61K 31/ 505^{( . )}
A61K 33/ 00^{( . )}
A61K 45/ 00^{( . )}
A61P 7/ 00^{( . )}
A61P 27/ 06^{( . )}

A61K 31/ 04^{( . )}
A61K 31/ 50^{( . )}
A61K 31/ 52^{( . )}
A61K 38/ 22^{( . )}
A61K 45/ 06^{( . )}
A61P 27/ 02^{( . )}
C07D 241/ 44^{( . )}

(86)	International application number:
	PCT/US1988/000168

(87)	International publication number:
	WO 1988/005306 (28.07.1988 Gazette 1988/17)

(84)	Designated Contracting States:
	AT BE CH DE FR GB IT LI LU NL SE

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Priority:

23.01.1987 US 19870006405

(60)	Divisional application:
	93202327.8 / 0583821

(71)	Applicant: THE GENERAL HOSPITAL CORPORATION
	Boston, MA 02114 (US)

(72)	Inventor:
	NATHANSON, James, A. Wellesley, MA 02181 (US)

(74)	Representative: Sheard, Andrew Gregory, et al
	Kilburn & Strode 30, John Street London WC1N 2DD London WC1N 2DD (GB)

(54)	ATRIOPEPTINS, GUANYLATE CYCLASE ACTIVATORS, AND PHOSPHODIESTERASE INHIBITORS AS TREATMENT FOR GLAUCOMA, HYDROCEPHALUS AND CEREBRAL EDEMA (CRANIAL FLUID VOLUME DYSFUNCTION)