(19)
(11) EP 0 341 303 A1

(12)

(43) Date of publication:
15.11.1989 Bulletin 1989/46

(21) Application number: 89900512.0

(22) Date of filing: 17.11.1988
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
A61K 49/ 00( . )
C07K 16/ 28( . )
C12N 5/ 10( . )
C12P 21/ 08( . )
G01N 33/ 577( . )
C12R 1/ 91( . )
A61K 39/ 395( . )
A61P 35/ 00( . )
C07K 16/ 30( . )
C12N 15/ 02( . )
G01N 33/ 566( . )
A61K 38/ 00( . )
(86) International application number:
PCT/US1988/004118
(87) International publication number:
WO 1989/005155 (15.06.1989 Gazette 1989/13)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 19.11.1987 US 19870123045

(71) Applicant: SCRIPPS CLINIC AND RESEARCH FOUNDATION
La Jolla California 92037-1093 (US)

(72) Inventor:
  • CHERESH, David, A.
    San Diego, CA 92117 (US)

(74) Representative: Fisher, Adrian John, et al 
CARPMAELS & RANSFORD 43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) MONOCLONAL ANTIBODY AGAINST THE RGD-DIRECTED ADHESION RECEPTOR OF ENDOTHELIAL CELLS