(19)
(11) EP 0 347 435 A1

(12)

(43) Date of publication:
27.12.1989 Bulletin 1989/52

(21) Application number: 88908543.0

(22) Date of filing: 01.09.1988
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 37/ 00( . )
C07K 14/ 00( . )
C07K 14/ 73( . )
C07K 16/ 28( . )
C12N 1/ 21( . )
C12N 15/ 09( . )
G01N 33/ 569( . )
C12R 1/ 91( . )
 A61K 39/ 395( . )
A61P 37/ 06( . )
C07K 14/ 725( . )
C07K 16/ 00( . )
C07K 19/ 00( . )
C12N 7/ 02( . )
C12P 21/ 02( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1988/002940
(87) International publication number:
WO 1989/001940 (09.03.1989 Gazette 1989/06)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 04.09.1987 US 19870094322
07.01.1988 US 19880141649

(71) Applicant: BIOGEN, INC.
Cambridge Massachusetts 02142 (US)

(72) Inventors:
  • FISHER, Richard, A.
    Brookline, MA 02146 (US)
  • GILBERT, Walter
    Cambridge, MA 02140 (US)
  • SATO, Vicki, L.
    Cambridge, MA 02138 (US)
  • FLAVELL, Richard, A.
    Killingworth, CT 06417 (US)
  • MARAGANORE, John, M.
    Tewksbury, MA 01876 (US)
  • LIU, Theresa, R.
    Milton, MA 02186 (US)

(74) Representative: Bannerman, David Gardner, et al 
Withers & Rogers 4 Dyer's Buildings Holborn
London, EC1N 2JT
London, EC1N 2JT (GB)

   


(54) DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS