(19)
(11) EP 0 348 440 A1

(12)

(43) Date of publication:
03.01.1990 Bulletin 1990/01

(21) Application number: 88905524.0

(22) Date of filing: 06.06.1988
(51) International Patent Classification (IPC): 
C07D 221/ 26( . )
A61K 31/ 47( . )
A61P 9/ 10( . )
A61K 31/ 445( . )
A61K 45/ 06( . )
A61P 25/ 00( . )
(86) International application number:
PCT/US1988/001839
(87) International publication number:
WO 1988/009605 (15.12.1988 Gazette 1988/27)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 05.06.1987 US 19870058337

(71) Applicant: MEDICIS CORPORATION
Washington, DC 20006 (US)

(72) Inventor:
  • FADEN, Alan, I.
    Mill Valley, CA 94941 (US)

(74) Representative: Sternagel, Hans-Günther, Dr., et al 
Patentanwälte Dr. Michael Hann Dr. H.-G. Sternagel Sander Aue 30
D-51465 Bergisch Gladbach
D-51465 Bergisch Gladbach (DE)

   


(54) TRAUMATIC AND ISCHEMIC BRAIN INJURY TREATMENT WITH OPIATE-RECEPTOR ANTAGONISTS