RENIN INHIBITORS CONTAINING A CYCLOPROPYL AMINO ACID AND/OR A CYCLOALKYL TRANSITION-STATE ANALOGUE - Patent 0349570

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(11)

EP 0 349 570 A1

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(43)	Date of publication:
	10.01.1990 Bulletin 1990/02

(21)	Application number: 88902695.0

(22)	Date of filing: 02.03.1988

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International Patent Classification (IPC):

C12N 9/ 99^{( . )}
A61P 9/ 12^{( . )}
C07D 233/ 54^{( . )}
C07D 401/ 12^{( . )}
C07K 5/ 06^{( . )}

A61K 38/ 55^{( . )}
C07C 237/ 06^{( . )}
C07D 233/ 64^{( . )}
C07K 5/ 02^{( . )}
C07K 14/ 81^{( . )}

(86)	International application number:
	PCT/US1988/000547

(87)	International publication number:
	WO 1988/007053 (22.09.1988 Gazette 1988/21)

(84)	Designated Contracting States:
	AT BE CH DE FR GB IT LI LU NL SE

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Priority:

09.03.1987 US 19870023404

(71)	Applicant: THE UPJOHN COMPANY
	Kalamazoo, Michigan 49001 (US)

(72)	Inventors:
	GAMMILL, Ronald, B. Kalamazoo, MI 49002 (US) HESTER, Jackson, B., Jr. Galesburg, MI 49053 (US)

(74)	Representative: Perry, Robert Edward, et al
	GILL JENNINGS & EVERY Broadgate House 7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)

(54)	RENIN INHIBITORS CONTAINING A CYCLOPROPYL AMINO ACID AND/OR A CYCLOALKYL TRANSITION-STATE ANALOGUE