(19)

(11)

EP 0 351 424 A1

(12)

(43) Date of publication: 24.01.1990 Bulletin 1990/04 (21) Application number: 88910043.0 (22) Date of filing: 24.11.1988

(51) International Patent Classification (IPC):  A61L 27/ 00( . ) A61L 17/ 00( . ) A61L 29/ 16( . ) A61F 2/ 00( . ) A61F 2/ 32( . ) A61F 2/ 36( . ) A61F 2/ 30( . ) A61L 27/ 54( . ) A61L 31/ 16( . ) A61F 2/ 28( . ) A61F 2/ 34( . ) (86) International application number: PCT/FI1988/000191 (87) International publication number: WO 1989/004674 (01.06.1989 Gazette 1989/12)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 26.11.1987 FI 19870005223 (71) Applicant: BIOCON OY SF-33710 Tampere (FI)	(72) Inventors: TÖRMÄLÄ, Pertti SF-33710 Tampere (FI) VAINIONPÄÄ, Seppo SF-00320 Helsinki (FI) ROKKANEN, Pentti SF-00930 Helsinki (FI) MERO, Matti SF-00830 Helsinki (FI) (74) Representative: Smulders, Theodorus A.H.J., Ir., et al  Vereenigde Octrooibureaux Nieuwe Parklaan 97 NL-2587 BN 's-Gravenhage NL-2587 BN 's-Gravenhage (NL)