(19)
(11) EP 0 352 299 A1

(12)

(43) Date of publication:
31.01.1990 Bulletin 1990/05

(21) Application number: 88904846.0

(22) Date of filing: 12.05.1988
(51) International Patent Classification (IPC): 
C12P 17/ 18( . )
A61K 31/ 70( . )
A61K 35/ 74( . )
C07D 498/ 06( . )
C12R 1/ 465( . )
A61K 31/ 535( . )
A61K 31/ 7042( . )
A61P 31/ 12( . )
C07H 17/ 00( . )
(86) International application number:
PCT/US1988/001493
(87) International publication number:
WO 1988/008707 (17.11.1988 Gazette 1988/25)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 15.05.1987 US 19870050823

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)

(72) Inventors:
  • REUSSER, Fritz
    Portage, MI 49081 (US)
  • BANNISTER, Brian
    Kalamazoo, MI 49008 (US)
  • TARPLEY, William, Gary
    Kalamazoo, MI 49008 (US)
  • ALTHAUS, Irene, W.
    Kalamazoo, MI 49008 (US)
  • ZAPOTOCKY, Barbara
    Ponte Vedra Beach, FL 32082 (US)

(74) Representative: Perry, Robert Edward, et al 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


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