(19)

(11)

EP 0 356 508 A1

(12)

(43) Date of publication: 07.03.1990 Bulletin 1990/10 (21) Application number: 89903397.0 (22) Date of filing: 14.02.1989

(51) International Patent Classification (IPC):  A61K 8/ 73( . ) A61Q 5/ 04( . ) A61K 8/ 81( . ) (86) International application number: PCT/US1989/000689 (87) International publication number: WO 1989/007435 (24.08.1989 Gazette 1989/20)

(84) Designated Contracting States: DE FR GB NL (30) Priority: 19.02.1988 US 19880157842 19.02.1988 US 19880157899 19.02.1988 US 19880158209 (71) Applicant: AMETHYST INVESTMENT GROUP, INC. Chicago, IL 60619 (US)	(72) Inventors: WILLIAMS, Barry, W. Chicago, IL 60619 (US) DANIELS, Pamela, M. Gary, IN 46407 (US) (74) Representative: Brooks, Nigel Samuel  Hill Hampton East Meon Petersfield Hampshire GU32 1QN Petersfield Hampshire GU32 1QN (GB)