(19)
(11) EP 0 357 641 A1

(12)

(43) Date of publication:
14.03.1990 Bulletin 1990/11

(21) Application number: 88903596.0

(22) Date of filing: 24.03.1988
(51) International Patent Classification (IPC): 
A61K 31/ 55( . )
A61P 25/ 18( . )
A61P 25/ 26( . )
C07D 223/ 32( . )
C07D 403/ 04( . )
A61P 25/ 04( . )
A61P 25/ 24( . )
C07D 223/ 16( . )
C07D 401/ 04( . )
C07D 521/ 00( . )
(86) International application number:
PCT/US1988/000899
(87) International publication number:
WO 1988/007526 (06.10.1988 Gazette 1988/22)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 27.03.1987 US 19870032135

(71) Applicant: SCHERING CORPORATION
Kenilworth New Jersey 07033 (US)

(72) Inventors:
  • BERGER, Joel, G.
    Cedar Grove, NJ 07009 (US)
  • CHANG, Wei, K.
    Livingston, NJ 07039 (US)
  • PETERS, Marjorie
    St. Simons Island, GA 31522 (US)

(74) Representative: von Kreisler, Alek, Dipl.-Chem., et al 
Patentanwälte von Kreisler-Selting-Werner Postfach 10 22 41
D-50462 Köln
D-50462 Köln (DE)

   


(54) SUBSTITUTED BENZAZEPINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM