(19)
(11)
EP 0 359 783 A1
(12)
(43)
Date of publication:
28.03.1990
Bulletin 1990/13
(21)
Application number:
88906457.0
(22)
Date of filing:
24.06.1988
(51)
International Patent Classification (IPC):
A61K
38/
17
( . )
A61K
39/
00
( . )
A61P
25/
00
( . )
A61P
37/
00
( . )
C07K
14/
46
( . )
A61K
38/
00
( . )
A61K
38/
39
( . )
A61K
39/
04
( . )
A61P
29/
00
( . )
C07K
7/
08
( . )
C07K
14/
47
( . )
A61K
38/
11
( . )
(86)
International application number:
PCT/US1988/002139
(87)
International publication number:
WO 1988/010120
(
29.12.1988
Gazette 1988/28)
(84)
Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
(30)
Priority:
24.06.1987
US 19870065734
(60)
Divisional application:
95102528.7 / 0666080
(71)
Applicant:
BRIGHAM AND WOMEN'S HOSPITAL
Boston, Massachusetts 02115 (US)
(72)
Inventors:
WEINER, Howard, L.
Brookline, MA 02146 (US)
HAFLER, David, A.
Newton, MA 02165 (US)
(74)
Representative:
Sheard, Andrew Gregory
Kilburn & Strode 30, John Street
London WC1N 2DD
London WC1N 2DD (GB)
(54)
TREATMENT OF AUTOIMMUNE DISEASES BY ORAL ADMINISTRATION OF AUTOANTIGENS