(19)

(11)

EP 0 362 277 A1

(12)

(43) Date of publication: 11.04.1990 Bulletin 1990/15 (21) Application number: 88905291.0 (22) Date of filing: 18.05.1988

(51) International Patent Classification (IPC):  A61K 9/ 00( . ) (86) International application number: PCT/US1988/001708 (87) International publication number: WO 1988/009665 (15.12.1988 Gazette 1988/27)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 01.06.1987 US 19870057417 (71) Applicant: ALLERGAN, INC Irvine, California 92715 (US)	(72) Inventor: CLARK, Donald, S. Laguna Hills, CA 92653 (US) (74) Representative: Hutchins, Michael Richard  Graham Watt & Co. London Road Riverhead Sevenoaks, Kent TN13 2BN Sevenoaks, Kent TN13 2BN (GB)