(19)
(11)
EP 0 366 669 A1
(12)
(43)
Date of publication:
09.05.1990
Bulletin 1990/19
(21)
Application number:
88904863.0
(22)
Date of filing:
13.05.1988
(51)
International Patent Classification (IPC):
C12N
9/
99
( . )
A61K
31/
496
( . )
A61K
31/
5355
( . )
A61K
31/
66
( . )
A61P
5/
38
( . )
A61P
9/
12
( . )
C07D
217/
24
( . )
C07D
235/
18
( . )
C07D
401/
12
( . )
C07K
14/
81
( . )
A61K
31/
495
( . )
A61K
31/
535
( . )
A61K
31/
5375
( . )
A61K
38/
55
( . )
A61P
9/
00
( . )
A61P
43/
00
( . )
C07D
233/
54
( . )
C07D
295/
18
( . )
C07K
5/
06
( . )
(86)
International application number:
PCT/US1988/001535
(87)
International publication number:
WO 1989/000161
(
12.01.1989
Gazette 1989/02)
(84)
Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
(30)
Priority:
29.06.1987
US 19870068095
(71)
Applicant:
THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)
(72)
Inventor:
THAISRIVONGS, Suvit
Portage, MI 49002 (US)
(74)
Representative:
Perry, Robert Edward, et al
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)
(54)
MALIC ACID DERIVATIVE CONTAINING RENIN INHIBITING PEPTIDES