(19)
(11) EP 0 366 669 A1

(12)

(43) Date of publication:
09.05.1990 Bulletin 1990/19

(21) Application number: 88904863.0

(22) Date of filing: 13.05.1988
(51) International Patent Classification (IPC): 
C12N 9/ 99( . )
A61K 31/ 496( . )
A61K 31/ 5355( . )
A61K 31/ 66( . )
A61P 5/ 38( . )
A61P 9/ 12( . )
C07D 217/ 24( . )
C07D 235/ 18( . )
C07D 401/ 12( . )
C07K 14/ 81( . )
A61K 31/ 495( . )
A61K 31/ 535( . )
A61K 31/ 5375( . )
A61K 38/ 55( . )
A61P 9/ 00( . )
A61P 43/ 00( . )
C07D 233/ 54( . )
C07D 295/ 18( . )
C07K 5/ 06( . )
(86) International application number:
PCT/US1988/001535
(87) International publication number:
WO 1989/000161 (12.01.1989 Gazette 1989/02)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 29.06.1987 US 19870068095

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)

(72) Inventor:
  • THAISRIVONGS, Suvit
    Portage, MI 49002 (US)

(74) Representative: Perry, Robert Edward, et al 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) MALIC ACID DERIVATIVE CONTAINING RENIN INHIBITING PEPTIDES