(19)
(11) EP 0 371 509 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
13.03.1991 Bulletin 1991/11

(43) Date of publication A2:
06.06.1990 Bulletin 1990/23

(21) Application number: 89122134.3

(22) Date of filing: 30.11.1989
(51) International Patent Classification (IPC)5: C07G 11/00, C12P 1/06, C12N 1/20, A61K 35/66
// C12P1:06, C12R1:465, C12N1:20, C12R1:465
(84) Designated Contracting States:
AT BE CH DE ES FR GB LI NL SE

(30) Priority: 01.12.1988 IT 2280888

(71) Applicant: MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA
I-00196 Roma (IT)

(72) Inventors:
  • Cidaria, Dante
    I-28100 Novara (IT)
  • Andriollo, Nunzio
    I-20021 Bollate Milan (IT)
  • Cassani, Giorgio
    I-20010 Arluno Milan (IT)
  • Crestani, Enrico
    I-28100 Novara (IT)
  • Spera, Silvia
    I-21020 Daverio Varese (IT)
  • Garavaglia, Carlo
    I-20012 Cuggiono Milan (IT)
  • Pirali, Giorgio
    I-21047 Saronno Varese (IT)
  • Confalonieri, Giovanni
    I-20052 Monza Milan (IT)

(74) Representative: Weinhold, Peter, Dr. et al
Patentanwälte Dr. Weinhold, Dannenberg, Dr. Gudel, Schubert Siegfriedstrasse 8
80803 München
80803 München (DE)


(56) References cited: : 
   
       


    (54) Antibiotics and process for producing them


    (57) The AB-021 antibiotics and the main components thereof, AB-021a antibiotic and AB-021b antibiotic, obtained by means of the controlled aerobic cultivation of Streptomyces s p. NCIB 40068 in an aqueous nutrient cultivation medium, are disclosed.
    Said antibiotics show a biological activity against patho­genic fungi of agrarian cultivations, pathogenic human fungi and bacteria.





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