(19)
(11) EP 0 378 615 A1

(12)

(43) Date of publication:
25.07.1990 Bulletin 1990/30

(21) Application number: 89906571.0

(22) Date of filing: 25.05.1989
(51) International Patent Classification (IPC): 
C07H 1/ 02( . )
C07H 19/ 10( . )
C07H 21/ 00( . )
C07H 21/ 04( . )
C07H 19/ 04( . )
C07H 19/ 20( . )
C07H 21/ 02( . )
(86) International application number:
PCT/US1989/002293
(87) International publication number:
WO 1989/011486 (30.11.1989 Gazette 1989/28)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 26.05.1988 US 19880198886
22.02.1989 US 19890314011

(71) Applicant: UNIVERSITY PATENTS, INCORPORATED
Westport, CT 06881 (US)

(72) Inventors:
  • CARUTHERS, Marvin
    Boulder, CO 80303 (US)
  • BRILL, Wolfgang
    Boulder, CO 80302 (US)
  • NIELSEN, John
    DK-2950 Vedbaek (DK)

(74) Representative: Allam, Peter Clerk, et al 
LLOYD WISE, TREGEAR & CO. Norman House 105-109 Strand
London WC2R 0AE
London WC2R 0AE (GB)

   


(54) NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES