(19)
(11) EP 0 378 643 A1

(12)

(43) Date of publication:
25.07.1990 Bulletin 1990/30

(21) Application number: 89907511.0

(22) Date of filing: 08.06.1989
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61K 38/ 55( . )
A61P 31/ 12( . )
A61K 38/ 17( . )
A61K 45/ 00( . )
A61P 31/ 18( . )
(86) International application number:
PCT/US1989/002453
(87) International publication number:
WO 1989/011860 (14.12.1989 Gazette 1989/29)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 10.06.1988 US 19880204645
20.04.1989 US 19890341080

(71) Applicants:
  • BIOGEN, INC.
    Cambridge Massachusetts 02142 (US)
  • THE GENERAL HOSPITAL CORPORATION
    Boston, MA 02114 (US)

(72) Inventors:
  • FISHER, Richard, A.
    Brookline, MA 02146 (US)
  • SCHOOLEY, Robert, T.
    Hingham, MA 02043 (US)
  • HIRSCH, Martin, S.
    Newton, MA 02158 (US)
  • JOHNSON, Victoria, A.
    Boston, MA 02116 (US)
  • WALKER, Bruce, D.
    Jamaica Plains, MA 02130 (US)

(74) Representative: Bannerman, David Gardner, et al 
Withers & Rogers 4 Dyer's Buildings Holborn
London, EC1N 2JT
London, EC1N 2JT (GB)

   


(54) COMBINATIONS OF SOLUBLE T4 PROTEINS AND ANTI-RETROVIRAL AGENTS AND METHODS FOR TREATING OR PREVENTING AIDS, ARC AND HIV INFECTION