DEFECTIVE HEPADNAVIRUSES AND PRODUCER CELL LINE FOR VACCINES AND TREATMENT OF LIVER DISEASES AND DISORDERS - Patent 0380656

(19)

(11)

EP 0 380 656 A1

(12)

(43)	Date of publication:
	08.08.1990 Bulletin 1990/32

(21)	Application number: 89910500.0

(22)	Date of filing: 16.08.1989

(51)

International Patent Classification (IPC):

A61K 39/ 29^{( . )}
C12N 15/ 86^{( . )}

C07K 14/ 02^{( . )}
A61K 38/ 00^{( . )}

(86)	International application number:
	PCT/US1989/003521

(87)	International publication number:
	WO 1990/002176 (08.03.1990 Gazette 1990/06)

(84)	Designated Contracting States:
	AT BE CH DE FR GB IT LI LU NL SE

(30)

Priority:

16.08.1988 US 19880232811

(71)	Applicants:
	YALE UNIVERSITY New Haven, CT 06520 (US) FOX CHASE CANCER CENTER Philadelphia Pennsylvania 19111 (US)

(72)	Inventors:
	HORWICH, Arthur, Louis Bradford, CT 06405 (US) SUMMERS, Jesse, William Placitas, NM 87043 (US)

(74)	Representative: Hale, Stephen Geoffrey
	J.Y. & G.W. Johnson Furnival House 14/18 High Holborn London WC1V 6DE London WC1V 6DE (GB)

(54)	DEFECTIVE HEPADNAVIRUSES AND PRODUCER CELL LINE FOR VACCINES AND TREATMENT OF LIVER DISEASES AND DISORDERS