(19)

(11)

EP 0 382 784 A1

(12)

(43) Date of publication: 22.08.1990 Bulletin 1990/34 (21) Application number: 89900075.0 (22) Date of filing: 21.10.1988

(51) International Patent Classification (IPC):  C12M 1/ 42( . ) C12M 3/ 00( . ) C12N 13/ 00( . ) C08G 61/ 12( . ) C12N 1/ 20( . ) (86) International application number: PCT/US1988/003737 (87) International publication number: WO 1989/003876 (05.05.1989 Gazette 1989/10)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 21.10.1987 US 19870111360 (71) Applicant: BIOSYN-R CORPORATION Philadelphia, PA 19123 (US)	(72) Inventor: SCHNEIDER, Barbara Philadelphia, PA 19118 (US) (74) Representative: Bassett, Richard Simon, et al  ERIC POTTER & CLARKSON St. Mary's Court St. Mary's Gate Nottingham NG1 1LE Nottingham NG1 1LE (GB)