(19)
(11)
EP 0 386 203 A1
(12)
(43)
Date of publication:
12.09.1990
Bulletin 1990/37
(21)
Application number:
89909553.0
(22)
Date of filing:
30.08.1989
(51)
International Patent Classification (IPC):
C12N
15/
09
( . )
C07K
14/
00
( . )
C07K
14/
59
( . )
C12N
5/
10
( . )
C12P
21/
00
( . )
C07K
1/
20
( . )
C07K
14/
575
( . )
C07K
19/
00
( . )
C12N
15/
16
( . )
C12R
1/
91
( . )
(86)
International application number:
PCT/EP1989/001017
(87)
International publication number:
WO 1990/002812
(
22.03.1990
Gazette 1990/07)
(84)
Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
(30)
Priority:
01.09.1988
US 19880239721
(71)
Applicant:
Applied Research Systems ARS Holding N.V.
CuraƧao (AN)
(72)
Inventors:
CHAPPEL, Scott, C.
Boston, MA 02114 (US)
NUGENT, Noreen, P.
Framingham, MA 01701 (US)
(74)
Representative:
Ritter, Stephen David, et al
Mathys & Squire 100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)
(54)
METHODS FOR PRODUCING GONADOTROPIN AND TSH SUPER-AGONISTS