(19)

(11)

EP 0 397 813 A1

(12)

(43) Date of publication: 22.11.1990 Bulletin 1990/47 (21) Application number: 89911635.0 (22) Date of filing: 24.10.1989

(51) International Patent Classification (IPC):  C12Q 1/ 34( . ) G01N 33/ 68( . ) C12Q 1/ 37( . ) (86) International application number: PCT/SE1989/000586 (87) International publication number: WO 1990/005192 (17.05.1990 Gazette 1990/11)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 03.11.1988 SE 19880003986 (71) Applicant: PHARMACIA AB S-751 82 Uppsala (SE)	(72) Inventors: AUFFRET, Anthony, David Cambridge CB4 4LJ (GB) AITKEN, Alastair Herts EN6 2LA (GB) FARRIES, Timothy, Charles Finchley London N3 2QB (GB) (74) Representative: Monsch, René, et al  E. BLUM & CO., Patentanwälte Vorderberg 11 CH-8044 Zürich CH-8044 Zürich (CH)