A NOVEL FAMILY OF HIGH AFFINITY, MODIFIED ANTIBODIES FOR CANCER TREATMENT - Patent 0397821

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(11)

EP 0 397 821 A1

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(43)	Date of publication:
	22.11.1990 Bulletin 1990/47

(21)	Application number: 89911974.0

(22)	Date of filing: 04.10.1989

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International Patent Classification (IPC):

G01N 33/ 574^{( . )}
A61K 31/ 70^{( . )}
A61K 39/ 395^{( . )}
A61K 47/ 48^{( . )}
A61K 51/ 10^{( . )}
C07H 21/ 04^{( . )}
C07K 16/ 00^{( . )}
C07K 16/ 46^{( . )}
C12N 5/ 10^{( . )}
C12N 15/ 13^{( . )}
C12P 21/ 08^{( . )}
G01N 33/ 577^{( . )}

A61K 31/ 495^{( . )}
A61K 38/ 00^{( . )}
A61K 45/ 00^{( . )}
A61K 51/ 00^{( . )}
A61P 35/ 00^{( . )}
C07K 14/ 00^{( . )}
C07K 16/ 30^{( . )}
C07K 19/ 00^{( . )}
C12N 15/ 09^{( . )}
C12P 21/ 00^{( . )}
G01N 33/ 531^{( . )}
C12R 1/ 91^{( . )}

(86)	International application number:
	PCT/US1989/004402

(87)	International publication number:
	WO 1990/004410 (03.05.1990 Gazette 1990/10)

(84)	Designated Contracting States:
	AT BE CH DE FR GB IT LI LU NL SE

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Priority:

19.10.1988 US 19880259943

(71)	Applicant: THE DOW CHEMICAL COMPANY (a Delaware corporation)
	Midland Michigan 48640 (US)

(72)	Inventors:
	MEZES, Peter Midland, MI 48640 (US) GOURLIE, Brian Midland, MI 48640 (US) RIXON, Mark Midland, MI 48640 (US)

(74)	Representative: Huber, Bernhard, Dipl.-Chem., et al
	Patentanwälte H. Weickmann, Dr. K. Fincke F.A. Weickmann, B. Huber Dr. H. Liska, Dr. J. Prechtel, Dr. B. Böhm Postfach 86 08 20 D-81635 München D-81635 München (DE)

(54)	A NOVEL FAMILY OF HIGH AFFINITY, MODIFIED ANTIBODIES FOR CANCER TREATMENT