(19)

(11)

EP 0 403 559 A1

(12)

(43) Date of publication: 27.12.1990 Bulletin 1990/52 (21) Application number: 89904148.0 (22) Date of filing: 03.03.1989

(51) International Patent Classification (IPC):  C07K 14/ 705( . ) C07K 16/ 30( . ) A61K 39/ 00( . ) C07K 16/ 28( . ) A61K 38/ 00( . ) (86) International application number: PCT/GB1989/000207 (87) International publication number: WO 1989/007947 (08.09.1989 Gazette 1989/21)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 04.03.1988 GB 19880005240 08.09.1988 GB 19880021078 (71) Applicant: CANCER RESEARCH CAMPAIGN TECHNOLOGY LTD. London SW1Y 5AR (GB)	(72) Inventors: STERN, Peter P.O. Box 147 Liverpool L69 3BX (GB) HOLE, Nicholas P.O. Box 147 Liverpool L69 3BX (GB) (74) Representative: Goldin, Douglas Michael, et al  J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)