(19)
(11) EP 0 407 416 A1

(12)

(43) Date of publication:
16.01.1991 Bulletin 1991/03

(21) Application number: 89903628.0

(22) Date of filing: 15.03.1989
(51) International Patent Classification (IPC): 
A61K 31/ 13( . )
A61K 31/ 38( . )
A61P 25/ 00( . )
A61P 25/ 26( . )
A61P 43/ 00( . )
C07C 323/ 38( . )
A61K 31/ 135( . )
A61K 31/ 381( . )
A61P 25/ 24( . )
A61P 25/ 28( . )
C07C 217/ 74( . )
C07D 333/ 20( . )
(86) International application number:
PCT/US1989/000974
(87) International publication number:
WO 1989/009050 (05.10.1989 Gazette 1989/24)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 25.03.1988 US 19880173130

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, MI 49001 (US)

(72) Inventors:
  • ANDERSSON, Bengt, Ronny
    S-437 00 Lindome (SE)
  • CARLSSON, Per, Arvid, Emil
    S-413 19 Goteborg (SE)
  • SVENSSON, Kjell, Anders, Ivan
    S-441 65 Allingas (SE)
  • WIKSTROM, Hakan, Vilhelm
    S-433 61 Partville (SE)

(74) Representative: Perry, Robert Edward, et al 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) THERAPEUTICALLY USEFUL TETRALIN DERIVATIVES