(19)
(11) EP 0 411 048 A1

(12)

(43) Date of publication:
06.02.1991 Bulletin 1991/06

(21) Application number: 89905928.0

(22) Date of filing: 26.04.1989
(51) International Patent Classification (IPC): 
C07D 221/ 16( . )
A61K 31/ 435( . )
A61K 31/ 473( . )
A61P 29/ 00( . )
C07D 221/ 08( . )
C07D 401/ 14( . )
C07D 491/ 044( . )
C07D 495/ 04( . )
C07F 9/ 59( . )
C07F 9/ 6561( . )
A61K 31/ 00( . )
A61K 31/ 47( . )
A61P 11/ 00( . )
A61P 37/ 08( . )
C07D 401/ 04( . )
C07D 491/ 04( . )
C07D 491/ 052( . )
C07F 9/ 576( . )
C07F 9/ 6509( . )
(86) International application number:
PCT/US1989/001688
(87) International publication number:
WO 1989/010369 (02.11.1989 Gazette 1989/26)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 28.04.1988 US 19880187604

(71) Applicant: SCHERING CORPORATION
Kenilworth New Jersey 07033 (US)

(72) Inventors:
  • PIWINSKI, John, J.
    Parsippany, NJ 07054 (US)
  • WONG, Jesse, K.
    Union, NJ 07083 (US)
  • GREEN, Michael, J.
    Skillman, NJ 08558 (US)
  • GANGULY, Ashit, K.
    Upper Montclair, NJ 07043 (US)
  • VILLANI, Frank, J.
    Fairfield, NJ 07006 (US)

(74) Representative: Ritter, Stephen David, et al 
Mathys & Squire 100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) NOVEL BENZOPYRIDO PIPERIDINE, PIPERIDYLIDENE AND PIPERAZINE COMPOUNDS, COMPOSITIONS, METHODS OF MANUFACTURE AND METHODS OF USE