(19)

(11)

EP 0 413 751 A1

(12)

(43) Date of publication: 27.02.1991 Bulletin 1991/09 (21) Application number: 89905913.0 (22) Date of filing: 02.05.1989

(51) International Patent Classification (IPC):  C07D 473/ 04( . ) A61K 31/ 52( . ) A61K 31/ 53( . ) A61P 25/ 00( . ) C07D 473/ 10( . ) A61K 31/ 4164( . ) A61K 31/ 522( . ) A61K 45/ 06( . ) C07D 473/ 08( . ) (86) International application number: PCT/US1989/001909 (87) International publication number: WO 1989/010744 (16.11.1989 Gazette 1989/27)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 02.05.1988 US 19880189464 (71) Applicant: NAFTCHI, N., Eric Teaneck, NJ 07666 (US)	(72) Inventor: NAFTCHI, N., Eric Teaneck, NJ 07666 (US) (74) Representative: VOSSIUS & PARTNER  Postfach 86 07 67 D-81634 München D-81634 München (DE)