5-OXA, 5-THIA, 5-AZA HMG-CoA REDUCTASE INHIBITORS - Patent 0422102

(19)

(11)

EP 0 422 102 A1

(12)

(43)	Date of publication:
	17.04.1991 Bulletin 1991/16

(21)	Application number: 89907935.0

(22)	Date of filing: 23.06.1989

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International Patent Classification (IPC):

A61K 31/ 335^{( . )}
A61K 31/ 38^{( . )}
A61K 31/ 47^{( . )}
A61P 9/ 10^{( . )}
C07D 215/ 233^{( . )}
C07D 311/ 74^{( . )}
C07D 405/ 06^{( . )}
C07D 409/ 06^{( . )}

A61K 31/ 365^{( . )}
A61K 31/ 382^{( . )}
A61P 3/ 06^{( . )}
C07D 215/ 22^{( . )}
C07D 311/ 22^{( . )}
C07D 335/ 06^{( . )}
C07D 407/ 06^{( . )}
C07F 9/ 6558^{( . )}

(86)	International application number:
	PCT/US1989/002805

(87)	International publication number:
	WO 1990/000053 (11.01.1990 Gazette 1990/02)

(84)	Designated Contracting States:
	CH DE FR GB IT LI NL

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Priority:

29.06.1988 US 19880212767
29.09.1988 US 19880250525

(71)	Applicant: MERCK & CO. INC.
	Rahway New Jersey 07065-0900 (US)

(72)	Inventors:
	DUGGAN, Mark, E. C101, Wynnewood, PA 19096 (US) HARTMAN, George, D. Lansdale, PA 19446 (US)

(74)	Representative: Hesketh, Alan, Dr.
	European Patent Department Merck & Co., Inc. Terlings Park Eastwick Road Harlow Essex, CM20 2QR Harlow Essex, CM20 2QR (GB)

(54)	5-OXA, 5-THIA, 5-AZA HMG-CoA REDUCTASE INHIBITORS