(19)
(11) EP 0 423 193 A1

(12)

(43) Date of publication:
24.04.1991 Bulletin 1991/17

(21) Application number: 89908043.0

(22) Date of filing: 07.07.1989
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61P 35/ 00( . )
C07K 14/ 52( . )
C07K 14/ 545( . )
C12R 1/ 19( . )
A61K 38/ 00( . )
A61P 37/ 04( . )
C07K 14/ 54( . )
C12P 21/ 00( . )
(86) International application number:
PCT/US1989/002904
(87) International publication number:
WO 1990/000563 (25.01.1990 Gazette 1990/03)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 07.07.1988 US 19880216418

(71) Applicants:
  • UNITED STATES GOVERNMENT, as represented by THE DEPARTMENT OF HEALTH & HUMAN SERVICES
    Bethesda, MD 20814 (US)
  • DAINIPPON PHARMACEUTICAL CO., LTD.
    Osaka-shi, Osaka 541 (JP)

(72) Inventors:
  • MATSUSHIMA, Kouji
    Frederick, MD 21701 (US)
  • LARSEN, Christian
    Frederick, MD 21701 (US)
  • OPPENHEIM, Joost
    Bethesda, MD 20892 (US)
  • SOHMURA, Yasunobu
    Osaka-fu (JP)

(74) Representative: Kraus, Walter, Dr., et al 
Patentanwälte Kraus, Weisert & Partner Thomas-Wimmer-Ring 15
D-80539 München
D-80539 München (DE)

   


(54) A METHOD OF TREATING DISEASES CAUSED BY IMMUNODEFICIENCY STATES BY ADMINISTERING HUMAN NEUTROPHIL CHEMOTACTIC FACTOR TO HUMAN