(19)
(11) EP 0 428 615 A1

(12)

(43) Date of publication:
29.05.1991 Bulletin 1991/22

(21) Application number: 89910335.0

(22) Date of filing: 09.08.1989
(51) International Patent Classification (IPC): 
C07K 14/ 47( . )
C07K 14/ 605( . )
C12N 1/ 21( . )
C12N 9/ 64( . )
C12P 21/ 06( . )
C07K 14/ 58( . )
C07K 14/ 785( . )
C12N 9/ 10( . )
C12P 21/ 02( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1989/003417
(87) International publication number:
WO 1990/001540 (22.02.1990 Gazette 1990/05)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 11.08.1988 US 19880231224

(71) Applicant: CALIFORNIA BIOTECHNOLOGY, INC.
Mountain View, CA 94043 (US)

(72) Inventors:
  • HILLIKER, Sandra
    Riverside, CA 92503 (US)
  • WHITE, R., Tyler
    Fremont, CA 94539 (US)

(74) Representative: Goldin, Douglas Michael, et al 
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) METHOD FOR STABILIZING HETEROLOGOUS PROTEIN EXPRESSION AND VECTORS FOR USE THEREIN