MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF - Patent 0431008

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EP 0 431 008 A1

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(43)	Date of publication:
	12.06.1991 Bulletin 1991/24

(21)	Application number: 89909473.0

(22)	Date of filing: 25.07.1989

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International Patent Classification (IPC):

C07D 487/ 04^{( . )}
A61P 35/ 00^{( . )}

A61K 31/ 40^{( . )}
C07D 487/ 14^{( . )}

(86)	International application number:
	PCT/US1989/003180

(87)	International publication number:
	WO 1990/001931 (08.03.1990 Gazette 1990/06)

(84)	Designated Contracting States:
	AT BE CH DE FR GB IT LI LU NL SE

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Priority:

23.08.1988 US 19880235224

(71)	Applicant: GEORGETOWN UNIVERSITY
	Washington, D.C. 20057 (US)

(72)	Inventors:
	TALEBIAN, Abdolhossen Herndon, VA 22070 (US) GREEN, Diana Falls Church, VA 22044 (US) HAMMER, Charles Washington, DC 20016 (US) SCHEIN, Philip, S. Bryn Mawr, PA 19010 (US)

(74)	Representative: Sheard, Andrew Gregory
	Kilburn & Strode 30, John Street London WC1N 2DD London WC1N 2DD (GB)

(54)	MITOMYCIN DERIVATIVES HAVING REDUCED BONE MARROW TOXICITY, PROCESSES FOR THEIR PREPARATION, AND THE USES THEREOF