(19)
(11) EP 0 434 714 A1

(12)

(43) Date of publication:
03.07.1991 Bulletin 1991/27

(21) Application number: 89909990.0

(22) Date of filing: 22.08.1989
(51) International Patent Classification (IPC): 
C07D 263/ 24( . )
A61K 31/ 421( . )
A61P 31/ 12( . )
C07D 263/ 20( . )
A61K 31/ 42( . )
A61P 31/ 04( . )
A61P 37/ 04( . )
C07D 413/ 04( . )
(86) International application number:
PCT/US1989/003548
(87) International publication number:
WO 1990/002744 (22.03.1990 Gazette 1990/07)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 15.09.1988 US 19880244988
05.10.1988 US 19880253850
17.03.1989 US 19890324942

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)

(72) Inventor:
  • BRICKNER, Steven, J.
    Portage, MI 49002 (US)

(74) Representative: Perry, Robert Edward, et al 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES