(19)
(11)
EP 0 434 714 A1
(12)
(43)
Date of publication:
03.07.1991
Bulletin 1991/27
(21)
Application number:
89909990.0
(22)
Date of filing:
22.08.1989
(51)
International Patent Classification (IPC):
C07D
263/
24
( . )
A61K
31/
421
( . )
A61P
31/
12
( . )
C07D
263/
20
( . )
A61K
31/
42
( . )
A61P
31/
04
( . )
A61P
37/
04
( . )
C07D
413/
04
( . )
(86)
International application number:
PCT/US1989/003548
(87)
International publication number:
WO 1990/002744
(
22.03.1990
Gazette 1990/07)
(84)
Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE
(30)
Priority:
15.09.1988
US 19880244988
05.10.1988
US 19880253850
17.03.1989
US 19890324942
(71)
Applicant:
THE UPJOHN COMPANY
Kalamazoo, Michigan 49001 (US)
(72)
Inventor:
BRICKNER, Steven, J.
Portage, MI 49002 (US)
(74)
Representative:
Perry, Robert Edward, et al
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)
(54)
IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES