(19)
(11) EP 0 435 877 A1

(12)

(43) Date of publication:
10.07.1991 Bulletin 1991/28

(21) Application number: 89909093.0

(22) Date of filing: 13.07.1989
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
C07K 7/ 08( . )
C07K 14/ 435( . )
C07K 14/ 81( . )
C07K 16/ 18( . )
C12N 15/ 09( . )
C12P 21/ 00( . )
G01N 33/ 577( . )
 C07H 21/ 04( . )
C07K 14/ 00( . )
C07K 14/ 47( . )
C07K 16/ 00( . )
C12N 5/ 10( . )
C12N 15/ 12( . )
C12P 21/ 08( . )
C12R 1/ 91( . )
(86) International application number:
PCT/US1989/003051
(87) International publication number:
WO 1990/000606 (25.01.1990 Gazette 1990/03)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 13.07.1988 US 19880224035

(71) Applicant: BRIGHAM AND WOMEN'S HOSPITAL
Boston, Massachusetts 02115 (US)

(72) Inventors:
  • STEVENS, Richard, L.
    250 Longwood Ave. Boston, MA 02115 (US)
  • WEIS, John, H.
    250 Longwood Ave. Boston, MA 02115 (US)
  • NICODEMUS, Christopher, F.
    Belmont, MA 02178 (US)

(74) Representative: Sheard, Andrew Gregory, et al 
Kilburn & Strode 30, John Street
London WC1N 2DD
London WC1N 2DD (GB)

   


(54) POLYNUCLEOTIDES THAT ENCODE THE HUMAN PROTEOGLYCAN PEPTIDE CORE OF THE EFFECTOR CELLS OF THE IMMUNE RESPONSE