(19)
(11) EP 0 435 957 A1

(12)

(43) Date of publication:
10.07.1991 Bulletin 1991/28

(21) Application number: 89911932.0

(22) Date of filing: 21.09.1989
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 35/ 00( . )
C07K 14/ 47( . )
C07K 16/ 18( . )
C12P 21/ 02( . )
C12Q 1/ 68( . )
A61K 39/ 395( . )
C07K 14/ 00( . )
C07K 16/ 00( . )
C12N 15/ 09( . )
C12P 21/ 08( . )
G01N 33/ 53( . )
(86) International application number:
PCT/US1989/004128
(87) International publication number:
WO 1990/003396 (05.04.1990 Gazette 1990/08)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 22.09.1988 US 19880247774

(71) Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Cambridge, MA 02139 (US)

(72) Inventors:
  • DONAHUE, Brian, A.
    Brighton, MA 02135 (US)
  • ESSIGMANN, John, M.
    Brookline, MA 02146 (US)
  • LIPPARD, Stephen, J.
    Cambridge, MA 02138 (US)
  • TONEY, Jeffrey, H.
    Cambridge, MA 02138 (US)

(74) Representative: Holdcroft, James Gerald, Dr., et al 
Graham Watt & Co., Riverhead
Sevenoaks, Kent TN13 2BN
Sevenoaks, Kent TN13 2BN (GB)

   


(54) DNA DAMAGE-BINDING FACTOR AND USES THEREFOR