(19)

(11)

EP 0 440 608 A1

(12)

(43) Date of publication: 14.08.1991 Bulletin 1991/33 (21) Application number: 89901434.0 (22) Date of filing: 14.12.1988

(51) International Patent Classification (IPC):  C07D 249/ 08( . ) C07D 521/ 00( . ) (86) International application number: PCT/US1988/004411 (87) International publication number: WO 1989/005801 (29.06.1989 Gazette 1989/14)

(84) Designated Contracting States: DE FR GB IT (30) Priority: 17.12.1987 US 19870134025 (71) Applicant: E.I. DU PONT DE NEMOURS AND COMPANY Wilmington Delaware 19898 (US)	(72) Inventors: BASARAB, Gregory, Steven Wilmington, DE 19802 (US) GREENBERG, Richard, Scot Fairlawn, NJ 07410 (US) (74) Representative: Hildyard, Edward Martin, et al  Frank B. Dehn & Co. European Patent Attorneys Imperial House 15-19 Kingsway London WC2B 6UZ London WC2B 6UZ (GB)