(19)

(11)

EP 0 441 842 A1

(12)

(43) Date of publication: 21.08.1991 Bulletin 1991/34 (21) Application number: 89912336.0 (22) Date of filing: 26.10.1989

(51) International Patent Classification (IPC):  A61F 13/ 15( . ) A61F 13/ 56( . ) (86) International application number: PCT/US1989/004783 (87) International publication number: WO 1990/004375 (03.05.1990 Gazette 1990/10)

(84) Designated Contracting States: AT BE CH DE FR GB IT LI LU NL SE (30) Priority: 27.10.1988 US 19880263529 (71) Applicant: McNEIL-PPC, Inc. Milltown New Jersey 08850 (US)	(72) Inventors: PIENIAK, Heinz, A. Des Moines, WA 89188 (US) HUFFMAN, Gloria Federal Way, WA 98003 (US) (74) Representative: Strehl Schübel-Hopf Groening & Partner  Maximilianstrasse 54 D-80538 München D-80538 München (DE)