(19)
(11) EP 0 449 871 A1

(12)

(43) Date of publication:
09.10.1991 Bulletin 1991/41

(21) Application number: 90900264.0

(22) Date of filing: 13.12.1989
(51) International Patent Classification (IPC): 
G01N 33/ 00( . )
A61K 31/ 5375( . )
A61K 31/ 546( . )
A61K 31/ 554( . )
C07B 61/ 00( . )
C07D 241/ 06( . )
C07D 267/ 08( . )
C07D 279/ 12( . )
C07D 501/ 00( . )
C07K 7/ 06( . )
A61K 31/ 535( . )
A61K 31/ 545( . )
A61K 31/ 55( . )
A61P 31/ 04( . )
C07D 223/ 06( . )
C07D 265/ 30( . )
C07D 273/ 06( . )
C07D 285/ 36( . )
C07K 1/ 00( . )
G01N 33/ 15( . )
(86) International application number:
PCT/GB1989/001493
(87) International publication number:
WO 1990/007111 (28.06.1990 Gazette 1990/15)
(84) Designated Contracting States:
AT BE CH DE ES FR GB IT LI LU NL SE

(30) Priority: 14.12.1988 US 19880284502

(71) Applicants:
  • HICKS, Richard
    Stubbs Cross, Ashford, Kent (GB)
  • QUEENS UNIVERSITY
    Kingston Ontario K7L 3N6 (CA)

(72) Inventors:
  • WOLFE, Saul
    Kingston, Ontario K7L 4V1 (CA)
  • BRUDER, Stephen
    Glenburnie, Ontaria K0H 1S0 (CA)

(74) Representative: Copp, David Christopher 
Dummett Copp & Co. 25 The Square Martlesham Heath
Ipswich Suffolk IP5 7SL
Ipswich Suffolk IP5 7SL (GB)

   


(54) METHOD FOR PREDICTING BIOLOGICAL ACTIVITY OF ANTIBIOTICS, AND NOVEL NON BETA-LACTAM ANTIBACTERIAL AGENTS DERIVED THEREFROM