(19)
(11) EP 0 451 145 A1

(12)

(43) Date of publication:
16.10.1991 Bulletin 1991/42

(21) Application number: 89909307.0

(22) Date of filing: 26.07.1989
(51) International Patent Classification (IPC): 
C07D 223/ 16( . )
C07C 209/ 00( . )
C07C 209/ 28( . )
C07C 211/ 42( . )
C07C 211/ 50( . )
C07C 213/ 08( . )
C07D 223/ 14( . )
C07B 61/ 00( . )
C07C 209/ 24( . )
C07C 209/ 70( . )
C07C 211/ 45( . )
C07C 211/ 57( . )
C07C 217/ 74( . )
(86) International application number:
PCT/US1989/003166
(87) International publication number:
WO 1990/001476 (22.02.1990 Gazette 1990/05)
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 29.07.1988 US 19880226304

(71) Applicant: SCHERING CORPORATION
Kenilworth New Jersey 07033 (US)

(72) Inventors:
  • BERGER, Joel, Gilbert
    Cedar Grove, NJ 07009 (US)
  • CLADER, John, Welch
    Cranford, NJ 07016 (US)

(74) Representative: Ritter, Stephen David, et al 
Mathys & Squire 100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) A PROCESS FOR THE ENANTIOSPECIFIC SYNTHESIS OF INTERMEDIATES FOR HEXAHYDRO-BENZO d]NAPHTHO 2,1-b]AZEPINES