(19)
(11) EP 0 451 869 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
08.07.1992 Bulletin 1992/28

(43) Date of publication A2:
16.10.1991 Bulletin 1991/42

(21) Application number: 91105883.2

(22) Date of filing: 12.04.1991
(51) International Patent Classification (IPC)5: A61K 31/565, C07J 1/00
(84) Designated Contracting States:
AT BE CH DE FR GB IT LI LU NL SE

(30) Priority: 12.04.1990 JP 97379/90

(71) Applicant: SNOW BRAND MILK PRODUCTS CO., LTD.
Sapporo-shi, Hokkaido 065 (JP)

(72) Inventors:
  • Fujise, Nobuaki
    Shimotsuga-gun, Tochigi-ken (JP)
  • Yamashita, Yasushi
    Shimotsuga-gun, Tochigi-ken (JP)
  • Takaoka, Hiroaki
    Shimotsuga-gun, Tochigi-ken (JP)
  • Honda, Nobuyoshi
    Shimotsuga-gun, Tochigi-ken (JP)
  • Yoshihama, Makoto
    Utsunomiya-shi, Tochigi-ken (JP)

(74) Representative: Hering, Hartmut, Dipl.-Ing. et al
Patentanwälte Berendt, Leyh & Hering Innere Wiener Strasse 20
D-81667 München
D-81667 München (DE)


(56) References cited: : 
   
       


    (54) Use of steroid derivatives in the treatment of endometriosis


    (57) A remedy for endometriosis comprising, as an active ingredient, 14a-hydroxy-4-androstene-3,6,17-trione or an ester derivative thereof, can effectively treat endometriosis by the strong aromatase-inhibitory activity without giving serious side effects.





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