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(11)

EP 0 454 778 A1

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(43)	Date of publication:
	06.11.1991 Bulletin 1991/45

(21)	Application number: 90902870.0

(22)	Date of filing: 12.01.1990

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International Patent Classification (IPC):

C12N 15/ 02^{( . )}
C07F 9/ 42^{( . )}
C12N 5/ 10^{( . )}
C12N 9/ 18^{( . )}
C12N 9/ 78^{( . )}
C12P 21/ 08^{( . )}

C07F 9/ 40^{( . )}
C07K 16/ 00^{( . )}
C12N 9/ 00^{( . )}
C12N 9/ 48^{( . )}
C12P 21/ 06^{( . )}
C12R 1/ 91^{( . )}

(86)	International application number:
	PCT/US1990/000269

(87)	International publication number:
	WO 1990/008185 (26.07.1990 Gazette 1990/17)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB IT LI LU NL SE

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Priority:

17.01.1989 US 19890297798

(71)	Applicant: SCRIPPS CLINIC AND RESEARCH FOUNDATION
	La Jolla, CA 92037 (US)

(72)	Inventors:
	LERNER, Richard La Jolla, CA 92037 (US) JANDA, Kim San Diego, CA 92107 (US) BENKOVIC, Stephen State College, PA 16801 (US)

(74)	Representative: Fisher, Adrian John, et al
	CARPMAELS & RANSFORD 43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)

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