(19)
(11)
EP 0 457 766 A1
(12)
(43)
Date of publication:
27.11.1991
Bulletin 1991/48
(21)
Application number:
90900678.0
(22)
Date of filing:
29.11.1989
(51)
International Patent Classification (IPC):
G01N
33/
15
( . )
C07K
14/
435
( . )
C07K
14/
72
( . )
C12N
5/
10
( . )
C12P
21/
00
( . )
C12R
1/
19
( . )
C07K
14/
00
( . )
C07K
14/
705
( . )
C12N
1/
21
( . )
C12N
15/
09
( . )
C12Q
1/
68
( . )
(86)
International application number:
PCT/US1989/005420
(87)
International publication number:
WO 1990/006364
(
14.06.1990
Gazette 1990/14)
(84)
Designated Contracting States:
AT BE CH DE ES FR GB IT LI LU NL
(30)
Priority:
30.11.1988
US 19880278606
(71)
Applicant:
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
La Jolla California 92037 (US)
(72)
Inventors:
EVAS, Ronald, Mark
La Jolla, CA 92037 (US)
ONG, Estelita, Sebastian
San Diego, CA 92117 (US)
ORO, Anthony, Eugene
San Diego, CA 92117 (US)
(74)
Representative:
UEXKÜLL & STOLBERG
Patentanwälte Beselerstrasse 4
D-22607 Hamburg
D-22607 Hamburg (DE)
(54)
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