(19)
(11) EP 0 457 837 A1

(12)

(43) Date of publication:
27.11.1991 Bulletin 1991/48

(21) Application number: 90903563.0

(22) Date of filing: 10.01.1990
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61K 9/ 50( . )
C07K 1/ 00( . )
C07K 14/ 61( . )
A61K 9/ 16( . )
A61K 38/ 27( . )
C07K 14/ 575( . )
(86) International application number:
PCT/US1990/000256
(87) International publication number:
WO 1990/008551 (09.08.1990 Gazette 1990/19)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB IT LI LU NL SE

(30) Priority: 26.01.1989 US 19890302410

(71) Applicant: ABBOTT BIOTECH, INC.
Needham Heights, MA 02194 (US)

(72) Inventors:
  • TSANG, Wen-Ghih
    Lexington, MA 02137 (US)
  • MAGEE, Andrew, S.
    Concord, MA 01742 (US)
  • SHYR, Ann, W.
    Newton Centre, MA 02159 (US)

(74) Representative: Harvey, David Gareth, et al 
Graham Watt & Co. Riverhead
Sevenoaks Kent TN13 2BN
Sevenoaks Kent TN13 2BN (GB)

   


(54) STABILIZATION OF AQUEOUS-BASED HYDROPHOBIC PROTEIN SOLUTIONS AND SUSTAINED RELEASE VEHICLE