(19)

(11)

EP 0 458 866 A1

(12)

(43) Date of publication: 04.12.1991 Bulletin 1991/49 (21) Application number: 90903600.0 (22) Date of filing: 15.02.1990

(51) International Patent Classification (IPC):  A61L 24/ 00( . ) A61L 24/ 04( . ) C08F 265/ 06( . ) C08L 33/ 04( . ) C09D 4/ 02( . ) A61K 6/ 083( . ) C08F 2/ 44( . ) C08K 7/ 02( . ) C08L 33/ 06( . ) C09D 4/ 06( . ) (86) International application number: PCT/GB1990/000249 (87) International publication number: WO 1990/009198 (23.08.1990 Gazette 1990/20)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 16.02.1989 GB 19890003565 (71) Applicant: NATIONAL RESEARCH DEVELOPMENT CORPORATION London SE1 6BU (GB)	(72) Inventor: GRAHAM, Neil, Bonnette Glasgow G61 3NY (GB) (74) Representative: Hamilton, Raymond  Patents Department British Technology Group Ltd 101 Newington Causeway London SE1 6BU London SE1 6BU (GB)