(19)
(11) EP 0 459 983 A1

(12)

(43) Date of publication:
11.12.1991 Bulletin 1991/50

(21) Application number: 90900649.0

(22) Date of filing: 15.12.1989
(51) International Patent Classification (IPC): 
C07D 265/ 24( . )
A61K 31/ 352( . )
A61K 31/ 443( . )
A61K 31/ 535( . )
A61P 9/ 10( . )
C07D 311/ 22( . )
C07D 405/ 06( . )
C07D 405/ 14( . )
C07D 413/ 06( . )
C07D 413/ 14( . )
C07D 417/ 12( . )
A61K 31/ 35( . )
A61K 31/ 44( . )
A61K 31/ 47( . )
A61K 31/ 536( . )
C07D 265/ 22( . )
C07D 405/ 04( . )
C07D 405/ 12( . )
C07D 413/ 04( . )
C07D 413/ 12( . )
C07D 417/ 04( . )
C07D 417/ 14( . )
(86) International application number:
PCT/US1989/005526
(87) International publication number:
WO 1990/006921 (28.06.1990 Gazette 1990/15)
(84) Designated Contracting States:
AT BE CH DE ES FR GB IT LI LU NL SE

(30) Priority: 21.12.1988 US 19880287796

(71) Applicant: THE UPJOHN COMPANY
Kalamazoo, MI 49001 (US)

(72) Inventors:
  • GAMMILL, Ronald, B.
    Kalamazoo, MI 49002 (US)
  • JUDGE, Thomas, M.
    Kalamazoo, MI 49001 (US)
  • MORRIS, Joel
    Kalamazoo, MI 49008 (US)

(74) Representative: Perry, Robert Edward, et al 
GILL JENNINGS & EVERY Broadgate House 7 Eldon Street
London EC2M 7LH
London EC2M 7LH (GB)

   


(54) ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES