(19)

(11)

EP 0 460 021 A1

(12)

(43) Date of publication: 11.12.1991 Bulletin 1991/50 (21) Application number: 90903634.0 (22) Date of filing: 01.02.1990

(51) International Patent Classification (IPC):  C07K 14/ 34( . ) C07K 14/ 73( . ) (86) International application number: PCT/US1990/000634 (87) International publication number: WO 1990/010015 (07.09.1990 Gazette 1990/21)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 23.02.1989 US 19890314369 (71) Applicant: SERAGEN, INC. Hopkinton, MA 01748 (US)	(72) Inventor: MURPHY, John, R. Wayland, MA 01778 (US) (74) Representative: Deans, Michael John Percy, et al  Lloyd Wise, Tregear & CO. Norman House 105-109 Strand London WC2R OAE London WC2R OAE (GB)