(19)

(11)

EP 0 460 102 A1

(12)

(43) Date of publication: 11.12.1991 Bulletin 1991/50 (21) Application number: 90904577.0 (22) Date of filing: 26.02.1990

(51) International Patent Classification (IPC):  C12Q 1/ 34( . ) G01N 33/ 543( . ) G01N 33/ 53( . ) G01N 33/ 564( . ) (86) International application number: PCT/US1990/001029 (87) International publication number: WO 1990/010229 (07.09.1990 Gazette 1990/21)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 27.02.1989 US 19890315567 (71) Applicant: BIOSTAR MEDICAL PRODUCTS INCORPORATED Boulder, CO 80301 (US)	(72) Inventors: LOPEZ, Luis, R. Aurora, CO 80014 (US) STERHAN, Marcia Louisville, CO 80027 (US) PETERSON, Tammy Broomfield, CO 80020 (US) (74) Representative: Sommerville, John Henry  SOMMERVILLE & RUSHTON 11 Holywell Hill St. Albans Hertfordshire, AL1 1EZ St. Albans Hertfordshire, AL1 1EZ (GB)